GenePage for the gtrS gene of Escherichia coli K-12

Primary Gene Name: gtrS
EcoGene Accession Number: EG14133
K-12 Gene Accession Number: ECK2346
MG1655 Gene Identifier: b2352
Gene Name Mnemonic: Glucosyl transferase
Alternate Gene Symbols: gtrIV; yfdI
Description: Serotype-specific glucosyl transferase, CPS-53/KpLE1 prophage; GtrIV(GtrS); part of the GtrABS tripartite system for prophage seroconversion of type IV O antigen to serotype 4a
  # bp Upstream # bp Downstream
MW: 51483.59 ---------443 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 2469131
Left Intergenic Region

Name: gtrB_gtrS

Length: 4 bp overlap

Orientation: Codirectional+

Left_end: 2469131

Right_end: 2469134

Centisome: 53.20

Genomic Address
Clockwise
Minute or Centisome (%) = 53.20
Right End: 2470462
Right Intergenic Region

Name: gtrS_tfaS

Length: 352 bp gap

Orientation: Codirectional+

Left_end: 2470463

Right_end: 2470814

Centisome: 53.22

GtrAB are highly conserved and the K-12 genes have been shown to be functional in partial converting Shigella flexneri serotype Y strain SFL124 to serotype 4a in conjunction with the serotype-specific glucosyl transferase GtrIV (GtrS) (Adams, 2001). Unlike highly conserved GtrAB, the CPS-53 GtrIV (GtrS) is quite divergent. The gtrIV gene nomenclature of Allison (2000) has been modified to conform to Demerec rules by droppingt he "EC" subscript and using the "S" one-letter code for CPS-53. The protein is referred to as GtrIV (GtrS). gtrS has a verified OxyR binding site within its coding region.

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BamHI EcoRI HindIII