GenePage for the yfgM gene of Escherichia coli K-12

Primary Gene Name: yfgM
EcoGene Accession Number: EG14209
K-12 Gene Accession Number: ECK2509
MG1655 Gene Identifier: b2513
Gene Name Mnemonic: Systematic nomenclature
Alternate Gene Symbols: None
Description: Ancillary SecYEG translocon subunit; putative anti-RcsB factor; membrane protein
  # bp Upstream # bp Downstream
MW: 22176.06 ---------206 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 2638663
Left Intergenic Region

Name: bamB_yfgM

Length: 10 bp gap

Orientation: Codirectional-

Left_end: 2638653

Right_end: 2638662

Centisome: 56.85

Genomic Address
Counterclockwise
Minute or Centisome (%) = 56.85
Right End: 2639283
Right Intergenic Region

Name: yfgM_hisS

Length: 17 bp gap

Orientation: Codirectional-

Left_end: 2639284

Right_end: 2639300

Centisome: 56.86

YfgM co- purifies with the SecYEG translocon and a yfgM deletion further compromises the integrity of the outer membrane in either a surA or skp mutant backgrounds (Götzke, 2014). YfgM overproduction decreases acid resistance like an rcsB mutation does, YfgM is degraded by FtsH, and YfgM may be an anti-RcsB factor (Westphal, 2012). HT_Cmplx42_Mem: RcsB+YfgM (Lasserre, 2006). A native membrane complex of YfgM and PpiD has been detected (Maddalo, 2011). YfgM may be ribosome associated (Jiang, 2007). 7/55 YfgM peptide masses from MS analysis confirm this start codon and indicate that the initial Met is not removed (Maillet, 2007). UPF0070 family.

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BamHI EcoRI HindIII