GenePage for the clpS gene of Escherichia coli K-12

Primary Gene Name: clpS
EcoGene Accession Number: EG14241
K-12 Gene Accession Number: ECK0872
MG1655 Gene Identifier: b0881
Gene Name Mnemonic: Caseinolytic protease
Alternate Gene Symbols: yljA
Description: Substrate modulator for ClpAP; directs protease activity towards aggregated proteins
  # bp Upstream # bp Downstream
MW: 12179.06 ---------106 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 922913
Left Intergenic Region

Name: cspD_clpS

Length: 322 bp gap

Orientation: Divergent

Left_end: 922591

Right_end: 922912

Centisome: 19.88

Genomic Address
Clockwise
Minute or Centisome (%) = 19.88
Right End: 923233
Right Intergenic Region

Name: clpS_clpA

Length: 30 bp gap

Orientation: Codirectional+

Left_end: 923234

Right_end: 923263

Centisome: 19.89

ClpS is needed for the degradation of N-end rule substrates by ClpAP. clpS is a non-essential gene. ClpS is homologous to eukaryotic E3 ubiquitin ligase n-recognin (Lupas, 2003).

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BamHI EcoRI HindIII