GenePage for the cydX gene of Escherichia coli K-12

Primary Gene Name: cydX
EcoGene Accession Number: EG14329
K-12 Gene Accession Number: ECK0723
MG1655 Gene Identifier: b4515
Gene Name Mnemonic: Cytochrome d
Alternate Gene Symbols: ybgT
Description: Cytochrome d (bd-I) ubiquinol oxidase subunit X; required for CydAB activity
  # bp Upstream # bp Downstream
MW: 4041.69 ---------37 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 774196
Left Intergenic Region

Name: cydB_cydX

Length: 14 bp gap

Orientation: Codirectional+

Left_end: 774182

Right_end: 774195

Centisome: 16.68

Genomic Address
Clockwise
Minute or Centisome (%) = 16.68
Right End: 774309
Right Intergenic Region

Name: cydX_ybgE

Length: 1 bp overlap

Orientation: Codirectional+

Left_end: 774309

Right_end: 774309

Centisome: 16.68

CydX(YbgT) binds to CydAB and is required for full cytochrome bd-I activity in cells; overproduced CbdX(AppX) can substitute for CydX in vivo (Vanorsdel; 2013). CydX(YbgT) and CbdX(AppX) are in cytochrome oxidase operons and have conserved cysteines that might help coordinate heme groups, although substitution C14S was functional, belying this proposition (Sun, 2012; Vanorsdel; 2013). YbgT was expressed in minicells at high temperature as a ~4 kDa protein, with no evidence of type I signal cleavage (Muller, 1997). Overexpression causes abnormal biofilm architecture and reduced motility. A false positive predicted 23 aa signal peptide cleavage would leave a 14 aa mature protein. cbdX(appX) and cydX(ybgT) are homologs.

Go to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePage

BamHI EcoRI HindIII