EcoGene

GenePage for the djlA gene of Escherichia coli K-12

Primary Gene Name: djlA
EcoGene Accession Number: EG11570
K-12 Gene Accession Number: ECK0056
MG1655 Gene Identifier: b0055

Common Core

CommonCore-5

Y-synonyms

Gene Name Mnemonic: DnaJ-like

Alternate Gene Symbols: yabH

Description:
DnaK co-chaperone, membrane-asssociated, DNA-binding; mutants rapidly accumulate suppressors

Pre-Run BlastP UniProt

Protein Sequence: ------------ MW: 30579.36------271 aa ------------ Pre-Run BlastP NR+Env

Genomic Address
Left End: 57364 ----------------- Clockwise ----------------- Right End: 58179
Left Inter Gene Info Minute or Centisome (%) = 1.24 Right Inter Gene Info

PDF EcoMap

Curator or user-submitted Comments:

DjlA overproduction activates RcsBC and Cps synthesis and causes mucoidy.  Normal levels of DjlA act as an Rcs negative regulator. The DjlA transmembrane domain is a dimerization domain.  DjlA has a single transmembrane domain and a C-terminal J-like domain. DjlA, CbpA, and DnaJ are all DNA-binding proteins, with the membrane bound cytosolic protein DjlA having high affinity for DNA (Gur, 2005).