EcoGene

GenePage for the nmpC' pseudogene of Escherichia coli K-12

Bacteriome: nmpC

CDD-COG: COG3203

CGSC: CG447

ChemGen Gene Correlations: nmpC

ChemGen Growth Data: nmpC

Gene-Profiles.org: nmpC

Genevestigator: P21420

GenExpDB: b0553

GenoBaseMG: b0553

Genome3D: P21420

GenomeReviews: P21420

GenPept-GenBank: AAC73654

Membranome: NMPC_ECOLI

MicrobesOnline: P21420

ProteomeFolding at YRC: P21420

ProtMap_COG: COG3203#NC_000913

ProtoNet: P21420

QUARK: E12346

QuickGO: P21420

RegulonDB-TU: ECK120014583

STRING: b0553

SWISS-2D: P21420

TCDB: P21420&tc=1.B.1.1.4

TCDB_Fam: 1.B.1

Transimulation: b0553

Unison: P21420

wikigenes: 946786

WolframAlpha: nmpC

xbase-ColiBASE: b0553

Primary Gene Name: nmpC'
EcoGene Accession Number: EG10659
K-12 Gene Accession Number: ECK0544
MG1655 Gene Identifier: b0553

DLP12 prophage

Interrupted Pseudogenes

Non-Core

Prophages

Pseudogenes

Reconstructed Pseudogenes

Signal Peptide Proteins

Verified Set

Verified Type I Signal Peptide Cleavages

Gene Name Mnemonic: New membrane protein

Alternate Gene Symbols: phmA

Description:
Pseudogene reconstruction, OM porin, DLP12 prophage; interrupted by IS5B

Pre-Run BlastP UniProt

Protein Sequence ------------ MW: 40302.38------365 aa ------------ Pre-Run BlastP NR+Env

Genomic Address

Left End: 574529 ----------------- Counterclockwise ----------------- Right End: 576825
Left Inter Gene Info Minute or Centisome (%) = 12.38 Right Inter Gene Info

PDF EcoMap

Curator or user-submitted Comments:

IS5B inserted at codon 347, causing a four base pair target site duplication TTAG and a C-terminal fusion ORF that is not expressed. The original, pre-insertion C-terminus is reconstructed, with KALGVSTDDIVAVGLVYQF replacing the IS5-encoded C-terminus KEGANKSLI. A 160 bp nmpC 3'-UTR is predicted to contain a predicted rho-indpendent terminator. 3'-UTR may contain ipeX sRNA (Castillo-Keller, 2006). nmpC mRNA and the putative ipeX downstream sRNA are silent in K-12. Overproduced ipeX RNA posttranslationally inhibits ompC and ompF.