EcoGene

GenePage for the nfuA gene of Escherichia coli K-12

APEX: 5011.15

Bacteriome: nfuA

ChemGen Gene Correlations: nfuA

ChemGen Growth Data: nfuA

Gene-Profiles.org: nfuA

Genevestigator: P63020

GenExpDB: b3414

Genome3D: P63020

GenomeReviews: P63020

GenPept: NP_417873.1

GenPept-GenBank: AAC76439

MicrobesOnline: P63020

ProteinOntology: 000023378

ProteomeFolding at YRC: P63020

TF Binding Sites: yhgI.html

xbase-ColiBASE: b3414

Primary Gene Name: nfuA
EcoGene Accession Number: EG12935
K-12 Gene Accession Number: ECK3401
MG1655 Gene Identifier: b3414

APEX

Cysteine Sulfenic Acid

Non-Core

Y-synonyms

Gene Name Mnemonic: NifU C-terminal domain-like

Alternate Gene Symbols: gntY, yhgI

Description:
Fe/S biogenesis protein; possible scaffold/chaperone for damaged Fe/S proteins

Pre-Run BlastP UniProt

Protein Sequence ------------ MW: 20997.70------191 aa ------------ Pre-Run BlastP NR+Env

Genomic Address
Left End: 3543646 ----------------- Clockwise ----------------- Right End: 3544221
Left Inter Gene Info Minute or Centisome (%) = 76.38 Right Inter Gene Info

PDF EcoMap

Curator or user-submitted Comments:

NfuA can transfer its [4Fe-4S] cluster into apo-aconitase AcnA and nfuA mutants have reduced survival to oxidative and iron stress (Angelini, 2008). nfuA(yhgI) is required for the utilization of DNA as a carbon source and is a H. influenzae competence protein ComG homolog (Palchevskiy, 2006). nfuA(gntY) does not have a role in gluconate metabolism (T.Conway, personal communication, 2000). iscA, sufA, and erpA are paralogs; nfuA is a possible HT gene with an N-terminal domain homologous to iscA and an additional thioredoxin-like C-terminal domain. IcsR regulon.