EcoGene

GenePage for the spy gene of Escherichia coli K-12

Bacteriome: spy

ChemGen Gene Correlations: spy

ChemGen Growth Data: spy

Gene-Profiles.org: spy

Genevestigator: P77754

GenExpDB: b1743

Genome3D: P77754

GenomeReviews: P77754

GenPept: NP_416257.1

GenPept-GenBank: AAC74813

MicrobesOnline: P77754

ProteinOntology: 000023981

ProteomeFolding at YRC: P77754

ProtoNet: P77754

QuickGO: P77754

RegulonDB-TU: ECK120016678

STRING: P77754

SWISS-2D: P77754

TF Binding Sites: spy.html

xbase-ColiBASE: b1743

Primary Gene Name: spy
EcoGene Accession Number: EG13490
K-12 Gene Accession Number: ECK1741
MG1655 Gene Identifier: b1743

Non-Core

Signal Peptide Proteins

Verified Set

Verified Type I Signal Peptide Cleavages

Gene Name Mnemonic: Spheroplast protein Y

Alternate Gene Symbols: None

Description:
Periplasmic ATP-independent protein refolding chaperone; dimeric

Pre-Run BlastP UniProt

Protein Sequence ------------ MW: 18199.07------161 aa ------------ Pre-Run BlastP NR+Env

Genomic Address
Left End: 1823164 ----------------- Counterclockwise ----------------- Right End: 1823649
Left Inter Gene Info Minute or Centisome (%) = 39.30 Right Inter Gene Info

PDF EcoMap

Curator or user-submitted Comments:

Spy is an ATP-independent chaperone that suppresses protein aggregation and aids protein refolding in the periplasm (Quan, 2011). Spy is induced by zinc and envelope stress, dependent on both CpxR and BaeSR. Spy and CpxP are paralogs.