EcoGene

GenePage for the rsxG gene of Escherichia coli K-12

Bacteriome: rsxG

ChemGen Gene Correlations: rsxG

ChemGen Growth Data: rsxG

Gene-Profiles.org: rsxG

Genevestigator: P77285

GenExpDB: b1631

Genome3D: P77285

GenomeReviews: P77285

GenPept: NP_416148.1

GenPept-GenBank: AAC74703

MicrobesOnline: P77285

ProteomeFolding at YRC: P77285

xbase-ColiBASE: b1631

Primary Gene Name: rsxG
EcoGene Accession Number: EG13937
K-12 Gene Accession Number: ECK1627
MG1655 Gene Identifier: b1631

Common Core

CommonCore-5

Y-synonyms

Gene Name Mnemonic: Reducer of SoxR

Alternate Gene Symbols: rnfG(R.c.), ydgP

Description:
Required for the reduction of SoxR; putative membrane protein

Pre-Run BlastP UniProt

Protein Sequence ------------ MW: 21911.91------206 aa ------------ Pre-Run BlastP NR+Env

Genomic Address
Left End: 1708228 ----------------- Clockwise ----------------- Right End: 1708848
Left Inter Gene Info Minute or Centisome (%) = 36.82 Right Inter Gene Info

PDF EcoMap

Curator or user-submitted Comments:

ApbE is probably required for a covalent flavination of conserved residues Thr187 in RsxD and Thr174 in RsxG with FMN, which then are likely to be required for the reduction of the 4Fe-4S cluster in ThiC in addition to the known Rsx function to reduce the 2Fe-2S cluster in SoxR. ApbE of Vibrio harveyi is a flavin transferase required for the covalent flavinylation of NqrC, an RsxG homolog, with FMN at position Thr229 (Bertsova, 2013). Vibrio cholerae RnfD (RsxD homolog) and RnfG (RsxG homolog) are covalently FMN flavinylated at residues Thr187 and Thr175, respectively (Backiel, 2008). Vibrio alginolyticus NqrC (RsxG homolog) and NqrB (RsxD homolog) are covalently FMN flavinylated at residues Thr223 and Thr235, respectively (Hayashi, 2001).