EcoGene

GenePage for the hipA gene of Escherichia coli K-12

Bacteriome: hipA

ChemGen Gene Correlations: hipA

ChemGen Growth Data: hipA

Gene-Profiles.org: hipA

Genevestigator: P23874

GenExpDB: b1507

Genome3D: P23874

GenomeReviews: P23874

GenPept: NP_416024.1

GenPept-GenBank: AAC74580

MicrobesOnline: P23874

ProteinOntology: 000022889

ProteomeFolding at YRC: P23874

ProtoNet: P23874

QUARK: E11793

QuickGO: P23874

RegulonDB-TU: ECK120014808

xbase-ColiBASE: b1507

Primary Gene Name: hipA
EcoGene Accession Number: EG10443
K-12 Gene Accession Number: ECK1500
MG1655 Gene Identifier: b1507

AUG Start Codons

Dif

Non-Core

Gene Name Mnemonic: High persistence

Alternate Gene Symbols: None

Description:
EF-Tu kinase; serine protein kinase required for persister formation; toxin of HipAB TA pair

Pre-Run BlastP UniProt

Protein Sequence ------------ MW: 49275.82------440 aa ------------ Pre-Run BlastP NR+Env

Genomic Address
Left End: 1588878 ----------------- Counterclockwise ----------------- Right End: 1590200
Left Inter Gene Info Minute or Centisome (%) = 34.25 Right Inter Gene Info

PDF EcoMap

Curator or user-submitted Comments:

HipA serine protein kinase autophosphorylates Ser150 and this activity is essential for persister formation (Correia, 2006). HipA binds and phosphorylates TufA/TufB residue Thr-383 (Schumacher, 2009). HipAB has a probable role in cell division.