EcoGene

GenePage for the lepB gene of Escherichia coli K-12

Bacteriome: lepB

ChemGen Gene Correlations: lepB

ChemGen Growth Data: lepB

Gene-Profiles.org: lepB

Genevestigator: P00803

GenExpDB: b2568

Genome3D: P00803

GenomeReviews: P00803

GenPept: NP_417063.1

GenPept-GenBank: AAC75621

MicrobesOnline: P00803

ProteinOntology: 000023080

ProteomeFolding at YRC: P00803

ProtoNet: P00803

QuickGO: P00803

RegulonDB-TU: ECK120014817

xbase-ColiBASE: b2568

Primary Gene Name: lepB
EcoGene Accession Number: EG10530
K-12 Gene Accession Number: ECK2566
MG1655 Gene Identifier: b2568

S26 Family Peptidases

Serine Peptidases

Gene Name Mnemonic: Leader peptidase

Alternate Gene Symbols: lep

Description:
Signal peptidase I; SPI; responsible for type I signal cleavages of periplasmic, OM, some IM, and extracellular proteins

Pre-Run BlastP UniProt

Protein Sequence ------------ MW: 35960.35------324 aa ------------ Pre-Run BlastP NR+Env

Genomic Address
Left End: 2702357 ----------------- Counterclockwise ----------------- Right End: 2703331
Left Inter Gene Info Minute or Centisome (%) = 58.24 Right Inter Gene Info

PDF EcoMap

Curator or user-submitted Comments:

LepB has a blocked N-terminus. False positive lipoprotein prediction, shown to have no signal peptide. Targetted by SRP/FtsY to Sec/YidC for membrane insertion.