EcoGene

GenePage for the malT gene of Escherichia coli K-12

Bacteriome: malT

ChemGen Gene Correlations: malT

ChemGen Growth Data: malT

Gene-Profiles.org: malT

Genevestigator: P06993

GenExpDB: b3418

Genome3D: P06993

GenomeReviews: P06993

GenPept: NP_417877.1

GenPept-GenBank: AAC76443

MicrobesOnline: P06993

ProteinOntology: 000023155

ProteomeFolding at YRC: P06993

ProtoNet: P06993

QuickGO: P06993

RegTransBase: 8813926

RegulonDB-TU: ECK120014899

STRING: P06993

SWISS-2D: P06993

TF Binding Sites: malT.html

xbase-ColiBASE: b3418

Primary Gene Name: malT
EcoGene Accession Number: EG10562
K-12 Gene Accession Number: ECK3405
MG1655 Gene Identifier: b3418

cAMP Input Functions

Common Core

CommonCore-5

Glycogen-deficiency ASKA clones

Predicted Regulons McCue 2002

Gene Name Mnemonic: Maltose

Alternate Gene Symbols: malA

Description:
ATP-dependent transcriptional activator for the mal regulon

Pre-Run BlastP UniProt

Protein Sequence ------------ MW: 103118.46------901 aa ------------ Pre-Run BlastP NR+Env

Genomic Address
Left End: 3551107 ----------------- Clockwise ----------------- Right End: 3553812
Left Inter Gene Info Minute or Centisome (%) = 76.54 Right Inter Gene Info

PDF EcoMap

Curator or user-submitted Comments:

Activated by maltotriose and ATP to form active oligomers. Signal transduction ATPases with numerous domains (STAND) protein. ATP hydrolysis is not required for transcription activation (Richet, 1989), but is required to recycle back to the inactive form, which has ADP, not ATP bound (Marquenet, 2007). MalY (Clausen, 2000; Schreiber, 2000), MalK (Reyes, 1988; Panagiotidis, 1998; Bohm, 2002) and Aes (Joly, 2002) negatively regulate MalT activity by binding and blocking maltotriose activation. MalT is required for phage lambda sensitivity.