EcoGene

GenePage for the relA gene of Escherichia coli K-12

Bacteriome: relA

ChemGen Gene Correlations: relA

ChemGen Growth Data: relA

Gene-Profiles.org: relA

Genevestigator: P0AG20

GenExpDB: b2784

Genome3D: P0AG20

GenomeReviews: P0AG20

GenPept: NP_417264.1

GenPept-GenBank: AAC75826

MicrobesOnline: P0AG20

ProteinOntology: 000023710

ProteomeFolding at YRC: P0AG20

TF Binding Sites: relA.html

xbase-ColiBASE: b2784

Primary Gene Name: relA
EcoGene Accession Number: EG10835
K-12 Gene Accession Number: ECK2778
MG1655 Gene Identifier: b2784

34 Active Assayable Promoters

Common Core

CommonCore-5

Stringent response and growth rate control

Gene Name Mnemonic: Relaxed

Alternate Gene Symbols: RC

Description:
ATP:GTP 3'-pyrophosphotransferase, ppGpp synthase I; GTP pyrophosphokinase; required for ppGpp synthesis during stringent response to amino acid starvation; self regulated

Pre-Run BlastP UniProt

Protein Sequence ------------ MW: 83875.62------744 aa ------------ Pre-Run BlastP NR+Env

Genomic Address
Left End: 2909439 ----------------- Counterclockwise ----------------- Right End: 2911673
Left Inter Gene Info Minute or Centisome (%) = 62.71 Right Inter Gene Info

PDF EcoMap

Curator or user-submitted Comments:

RelA has two physically and functionally distinct domains, the N-terminal domain, amino acids 1 to 455, is responsible for (p)ppGpp synthesis, and the C-terminal domain, amino acids 456 to 744, is responsible for self regulation.