EcoGene

GenePage for the slt gene of Escherichia coli K-12

Bacteriome: slt

ChemGen Gene Correlations: slt

ChemGen Growth Data: slt

Gene-Profiles.org: slt

Genevestigator: P0AGC3

GenExpDB: b4392

Genome3D: P0AGC3

GenomeReviews: P0AGC3

GenPept: NP_418809.4

GenPept-GenBank: AAC77345

MicrobesOnline: P0AGC3

ProteinOntology: 000023956

ProteomeFolding at YRC: P0AGC3

TF Binding Sites: slt.html

xbase-ColiBASE: b4392

Primary Gene Name: slt
EcoGene Accession Number: EG10950
K-12 Gene Accession Number: ECK4384
MG1655 Gene Identifier: b4392

Common Core

CommonCore-5

Murein hydrolases

Signal Peptide Proteins

Verified Set

Verified Type I Signal Peptide Cleavages

Gene Name Mnemonic: Soluble lytic transglycosylase

Alternate Gene Symbols: sltY

Description:
Soluble lytic murein transglycosylase Slt70, major autolysin, periplasmic

Pre-Run BlastP UniProt

Protein Sequence ------------ MW: 73353.15------645 aa ------------ Pre-Run BlastP NR+Env

Genomic Address
Left End: 4628756 ----------------- Clockwise ----------------- Right End: 4630693
Left Inter Gene Info Minute or Centisome (%) = 99.76 Right Inter Gene Info

PDF EcoMap

Curator or user-submitted Comments:

MltB is a soluble endolytic transglycosylase and an exolytic transglycosylase that can degrade both non-crosslinked and crosslinked murein chains (Lee, 2013). Slt cleaves the glycosidic bonds between the N-acetylmuramic acid and N-acetylglucosamine residues in murein. Slt has a C-terminal lysozyme-like domain.