EcoGene

GenePage for the tnaA gene of Escherichia coli K-12

Bacteriome: tnaA

ChemGen Gene Correlations: tnaA

ChemGen Growth Data: tnaA

Gene-Profiles.org: tnaA

Genevestigator: P0A853

GenExpDB: b3708

Genome3D: P0A853

GenomeReviews: P0A853

GenPept: NP_418164.4

GenPept-GenBank: AAC76731

MicrobesOnline: P0A853

ProteinOntology: 000024075

ProteinOntology: 000025239

ProteomeFolding at YRC: P0A853

ProtoNet: P0A853

QuickGO: P0A853

RegTransBase: 8815280

RegulonDB-TU: ECK120014894

STRING: P0A853

SWISS-2D: P0A853

TF Binding Sites: tnaA.html

xbase-ColiBASE: b3708

Primary Gene Name: tnaA
EcoGene Accession Number: EG11005
K-12 Gene Accession Number: ECK3701
MG1655 Gene Identifier: b3708

7 Stalled Complexes

BioFilm1

Glycogen-deficiency ASKA clones

Non-Core

Planktonic Genes

Protein Lysine Acetylation: Yu, 2008

Verified Set

Verified Translation Starts (no Met)

Verified Translation Starts Sites

Gene Name Mnemonic: Tryptophanase

Alternate Gene Symbols: ind

Description:
Tryptophanase, also has cysteine desulfhydrase activity; interconverts tryptophan and indole; also called L-tryptophan indole-lyase

Pre-Run BlastP UniProt

Protein Sequence ------------ MW: 52773.46------471 aa ------------ Pre-Run BlastP NR+Env

Genomic Address
Left End: 3886753 ----------------- Clockwise ----------------- Right End: 3888168
Left Inter Gene Info Minute or Centisome (%) = 83.77 Right Inter Gene Info

PDF EcoMap

Curator or user-submitted Comments:

TnaA is required for growth on tryptophan as a carbon source and indole as a tryptophan source. TnaA is a key enzyme in L-cysteine degradation. Alkali-inducible. Downregulated during cold-shock and in early exponential phase. Binds TrxA (Kumar, 2004). TnaA binds plasmid colE1 sRNA Rcd, which modulates TnaA activity to regulate growth inhibition by Rcd for plasmid stabilzation (Chant, 2007).