EcoGene

GenePage for the tyrA gene of Escherichia coli K-12

APEX: 770.66

Bacteriome: tyrA

ChemGen Gene Correlations: tyrA

ChemGen Growth Data: tyrA

Gene-Profiles.org: tyrA

Genevestigator: P07023

GenExpDB: b2600

Genome3D: P07023

GenomeReviews: P07023

GenPept: NP_417091.1

GenPept-GenBank: AAC75649

MicrobesOnline: P07023

ProteinOntology: 000024150

ProteomeFolding at YRC: P07023

ProtoNet: P07023

QuickGO: P07023

RegulonDB-TU: ECK120015038

xbase-ColiBASE: b2600

Primary Gene Name: tyrA
EcoGene Accession Number: EG11039
K-12 Gene Accession Number: ECK2597
MG1655 Gene Identifier: b2600

APEX

Horizontal Gene Transfer

HT1006

Oxidized Proteins

Oxidized Proteins, Phosphate

Verified Set

Verified Translation Starts (+Met)

Verified Translation Starts Sites

Gene Name Mnemonic: Tyrosine

Alternate Gene Symbols: None

Description:
Tyrosine synthesis: chorismate mutase/prephenate dehydrogenase

Pre-Run BlastP UniProt

Protein Sequence ------------ MW: 42042.52------373 aa ------------ Pre-Run BlastP NR+Env

Genomic Address
Left End: 2736970 ----------------- Counterclockwise ----------------- Right End: 2738091
Left Inter Gene Info Minute or Centisome (%) = 58.99 Right Inter Gene Info

PDF EcoMap

Curator or user-submitted Comments:

Bifunctional protein, mutase is N-terminal domain. TyrR regulon. tyrA is in the PurR regulon (Marbach, 2012). N-terminal protein sequencing identified a faint band of uncleaved precursor, indicating that some TyrA protein is not processed (Hudson, 1984). 2/904 TyrA peptide masses from MS analysis confirm this start codon and indicate that the initial Met is removed; 1/904 peptide masses indicate that occasionally the initial Met is not removed (Maillet, 2007).