EcoGene

GenePage for the mnmA gene of Escherichia coli K-12

Bacteriome: mnmA

CDD-COG: COG0482

CGSC: CG37613

ChemGen Gene Correlations: mnmA

ChemGen Growth Data: mnmA

Gene-Profiles.org: mnmA

Genevestigator: P25745

GenExpDB: b1133

GenoBaseMG: b1133

Genome3D: P25745

GenomeReviews: P25745

GenPept-GenBank: AAC74217

GenPept-RefSeq: NP_415651.4

Inparanoid: NP_415651.4

iProClass: P25745

iRefWeb: 945690

MicrobesOnline: P25745

ProteinOntology: 000023254

ProteomeFolding at YRC: P25745

ProtMap_COG: COG0482#NC_000913

Textpresso y-syn: ycfB

TIGR-CMR: NT01EC1379

Transimulation: b1133

Unison: P25745

wikigenes: 945690

WolframAlpha: mnmA

xbase-ColiBASE: b1133

Primary Gene Name: mnmA
EcoGene Accession Number: EG11344
K-12 Gene Accession Number: ECK1119
MG1655 Gene Identifier: b1133

Gene Name Mnemonic: Methyl-amino(N)-Methyl

Alternate Gene Symbols: asuE, trmU, ycfB

Description:
tRNA(Gln,Lys,Glu) U34 2-thiouridylase; first step in mnm(5)-s(2)U34-tRNA synthesis; TusE binding partner; antisuppressor

Pre-Run BlastP UniProt

Protein Sequence ------------ MW: 40959.43------368 aa ------------ Pre-Run BlastP NR+Env

Genomic Address
Left End: 1192667 ----------------- Counterclockwise ----------------- Right End: 1193773
Left Inter Gene Info Minute or Centisome (%) = 25.71 Right Inter Gene Info

PDF EcoMap

Curator or user-submitted Comments:

Sulfur may be donated to tRNA U34 from TusD-activated MnmA or from TusD directly. Arigoni(1998) reported that mnmA(ycfB) is an essential gene, however Dassain(1999) and Kambampati(2003) both found mnmA(ycfB) deletion mutants to grow slowly. MnmA was originally thought to be a methyltransferase and was named TrmU.