Escherichia coli K-12 GenePage Master Page of ftsH
GenePage for the
ftsH
gene of
Escherichia coli
K-12
Bacteriome: ftsH
CDD-COG: COG0465
CGSC: CG735
ChemGen Gene Correlations: ftsH
ChemGen Growth Data: ftsH
CMR: P0AAI3
Colibri: ftsH
COMBREX: 947690
DDBJ: AAC76210
Doodle: b3178
ECDC: CG02705
EchoBASE: EB1469
EchoLOCATION: EB1469
ECID: P0AAI3
ECMDB: P0AAI3
EcoliWiki: ftsH
eggNOG: P0AAI3
EMBL: AAC76210
ENZYME: 3.4.24.-
eSOL: JW3145
Gene-Profiles.org: ftsH
Genevestigator: P0AAI3
GenExpDB: b3178
GenoBaseMG: b3178
Genome3D: P0AAI3
GenomeReviews: P0AAI3
GenPept-GenBank: AAC76210
GenPept-RefSeq: NP_417645.1
GenProtEC: b3178
GORBI: 947690
GREMLIN: P0AAI3
iHOP: 947690
Inparanoid: NP_417645.1
iProClass: P0AAI3
iRefWeb: 947690
Membranome: FTSH_ECOLI
MEROPS: M41.001
MicrobesOnline: P0AAI3
MiST: 1584417
ModBase: P0AAI3
OMA: P0AAI3
Orthology.org: 61
PairsDB: P0AAI3
PATRIC: 32121774
PDB-UniProt: P0AAI3
Pedant: 1219
Predicted Regulons: E4028
PrFEct-Predict: ftsH
ProDom: P0AAI3
ProteinOntology: 000022717
ProteomeFolding at YRC: P0AAI3
ProtMap_COG: COG0465#NC_000913
ProtoNet: P0AAI3
QUARK: E11585
QuickGO: P0AAI3
STRING: b3178
SWISS-2D: P0AAI3
TF Binding Sites: hflB.html
Transimulation: b3178
Unison: P0AAI3
wikigenes: 947690
WolframAlpha: ftsH
xbase-ColiBASE: b3178
Primary Gene Name:
ftsH
EcoGene Accession Number: EG11506
K-12 Gene Accession Number: ECK3167
MG1655 Gene Identifier:
b3178
AAA+ ATPases
AUG Start Codons
Common Core
CommonCore-5
Essential Genes
IMemProt_Ei
InnerMemProt
M41 Family Peptidases
Metallo Peptidases
OM Proteome Lopez2005
Peptidase Families
Predicted Regulons McCue 2002
Protein Lysine Acetylation: Yu, 2008
Total Proteome Lopez2005
Gene Name Mnemonic: Filamentation, temperature sensitive
Alternate Gene Symbols: hflB, mrsC, std, tolZ
DNA Sequence
  # bp Upstream
# bp Downstream
Description:
ATP-dependent membrane protease, complexed with HflCK; regulates lysogeny; mutants are defective in cell growth, septum formation and phage lambda development; mutants rescued by divalent cations; binds Zn(II); hexameric
Pre-Run BlastP UniProt
Protein Sequence
------------ MW: 70708.09------644 aa ------------
Pre-Run BlastP NR+Env
Genomic Address
Left End: 3325001 ----------------- Counterclockwise ----------------- Right End: 3326935
Left Inter Gene Info
Minute or Centisome (%) = 71.66
Right Inter Gene Info
 
gene or min(Cs)
PDF EcoMap
Curator or user-submitted Comments:
HtpX collaborates with FtsH to eliminate abnormal membrane proteins: an hflX ftsH double mutant is temperature sensitive for growth. FtsH degrades both cytoplasmic, e.g. phage lambda cII protein, and membrane, e.g. SecY, substrates.
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