EcoGene

GenePage for the thiE gene of Escherichia coli K-12

Bacteriome: thiE

ChemGen Gene Correlations: thiE

ChemGen Growth Data: thiE

Gene-Profiles.org: thiE

Genevestigator: P30137

GenExpDB: b3993

Genome3D: P30137

GenomeReviews: P30137

GenPept: NP_418421.1

GenPept-GenBank: AAC76967

MicrobesOnline: P30137

ProteinOntology: 000024054

ProteomeFolding at YRC: P30137

ProtoNet: P30137

QuickGO: P30137

RegulonDB-TU: ECK120014652

xbase-ColiBASE: b3993

Primary Gene Name: thiE
EcoGene Accession Number: EG11586
K-12 Gene Accession Number: ECK3985
MG1655 Gene Identifier: b3993

Common Core

CommonCore-5

Tail-anchored Membrane Proteins

Gene Name Mnemonic: Thiamin (and thiazole)

Alternate Gene Symbols: thiA

Description:
Thiamin phosphate synthase; thiamine phosphate pyrophosphorylase, TMP-PPase; thiamin-thiazole moiety synthesis

Pre-Run BlastP UniProt

Protein Sequence ------------ MW: 23015.28------211 aa ------------ Pre-Run BlastP NR+Env

Genomic Address
Left End: 4191592 ----------------- Counterclockwise ----------------- Right End: 4192227
Left Inter Gene Info Minute or Centisome (%) = 90.34 Right Inter Gene Info

PDF EcoMap

Curator or user-submitted Comments:

The ThiE sequence has been confirmed using MS/MS: the measured mass of the intact protein is 23014.8 indicating that the initial Met is not clipped (Kelleher, 1998). No pmid: Backstrom AD, Austin R., McMordie S, Begley TP (1995) Biosynthesis of thiamin I: the function of the thiE gene product. J. Am. Chem. Soc. 117:2351-2. yjbQ is a multicopy suppressor of thiE (Morett, 2008).