EcoGene

GenePage for the ibaG gene of Escherichia coli K-12

Bacteriome: ibaG

ChemGen Gene Correlations: ibaG

ChemGen Growth Data: ibaG

Gene-Profiles.org: ibaG

Genevestigator: P0A9W6

GenExpDB: b3190

GenoBaseMG: b3190

Genome3D: P0A9W6

GenomeReviews: P0A9W6

GenPept-GenBank: AAC76222

GenPept-RefSeq: NP_417657.2

Inparanoid: NP_417657.2

iProClass: P0A9W6

iRefWeb: 947958

MicrobesOnline: P0A9W6

ProteomeFolding at YRC: P0A9W6

TF Binding Sites: yrbA.html

TIGR-CMR: NT01EC3852

Transimulation: b3190

Unison: P0A9W6

wikigenes: 947958

WolframAlpha: ibaG

xbase-ColiBASE: b3190

Primary Gene Name: ibaG
EcoGene Accession Number: EG12796
K-12 Gene Accession Number: ECK3179
MG1655 Gene Identifier: b3190

AUG Start Codons

Non-Core

Y-synonyms

Gene Name Mnemonic: Influenced By Acid Gene

Alternate Gene Symbols: yrbA

Description:
Acid stress protein; predicted transcriptional regulator, BolA family; low abundance protein

Pre-Run BlastP UniProt

Protein Sequence ------------ MW: 9451.74------84 aa ------------ Pre-Run BlastP NR+Env

Genomic Address
Left End: 3336549 ----------------- Counterclockwise ----------------- Right End: 3336803
Left Inter Gene Info Minute or Centisome (%) = 71.91 Right Inter Gene Info

PDF EcoMap

Curator or user-submitted Comments:

A ibaG(yrbA) mutant is sensitive to acid stress; ibaG(yrbA) transcription is induced by acid stress; overexpression of IbaG(YrbA) improves acid resistance (Guinote, 2012). Overexpression of ibaG(yrbA), which is paralogous to the morphogene bolA, is toxic; an insertion in the upstream gene mlaB(yrbB) can be deleterious due to increased expression of ibaG(yrbA), which is why the non-essential mlaB(yrbB) gene does not have a kan insertion in the Keio collection (Malinverni, 2009). grxD mutations are synthetic lethal with mutations in the isc operon, suggesting that Grx4 is involved in an alternative FeS cluster assembly pathway; a similar synthetic lethality pattern was observed for the bolA-like gene ibaG(yrbA), but not for bolA (Butland, 2005).