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TopicPage for A:C mismatch binding of Escherichia coli K-12

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Proteome Chips: Mismatch Binding         

Description:

Chen (2008) identified the top 20 proteins that preferentially bind to dsDNA containing an A:C mismatch, called probe 2. Probe 1 is the same 19-mer without the mismatch on the lower strand.

Details:

5'-GGAATTAAAGCGAAGACC-3'
3'- CCTTAATTTCACTTCTGG-5

The ratio of the preferential probe 2 binding ranges from 2.2 fold for CitF to 1.8 fold for YfeP.


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