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TopicPage for cAMP Input Functions of Escherichia coli K-12

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Regulatory Modeling Regulon         


The cAMP input functions, which are the relations between input signals and transcription rates, for nineteen sugar genes regulated by CRP-cAMP and five sugar-specific regulators AraC, GalS, MalT, RhaS and FucR were measured (Kaplan, 2008).


Figure 1 illustrates the regulatory circuitry, which is termed a dense overlapping regulon (DOR) network motif. Figure 2 shows the input function plots. The operons are represented by their promoter proximal genes in EcoGene.

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