Welcome to !

EcogeneTopic Page

TopicPage for thiB 5' UTR of Escherichia coli K-12

View Genes On Map

Riboswitches         

Description:

thiBPQ operon expression is controlled by a thiamine pyrophosphate (TPP) responsive riboswitch in the 128 nt 5' UTR. This THI element has been reported in intergenic sRNA searches as sroA/tpe79. The thiB riboswitch is the target for the antibiotic pyrithiamine.

Details:

The attenuation of transcription at the TPP-bound riboswitch produces the 93 nt sroA sRNA, ending at 75608.


Bibliography (4 total) : Review Only   Up