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TopicPage for Bar-coded DNA Repair Mutants of Escherichia coli K-12

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DNA Repair Keio Mutant Validations         

Description:

Rooney (2008) created a set of 99 bar-coded deletions in genes involved in DNA damage and repair.

Details:

The deletions are marked with chloramphenicol resistance cassettes.

Rooney (2009) compared the phenotypes of their bar-coded mutants with mutants in the same genes from the Keio collection and found 90% had the same phenotype.


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