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TopicPage for Bar-coded DNA Repair Mutants of Escherichia coli K-12

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DNA Repair Keio Mutant Validations         


Rooney (2008) created a set of 99 bar-coded deletions in genes involved in DNA damage and repair.


The deletions are marked with chloramphenicol resistance cassettes.

Rooney (2009) compared the phenotypes of their bar-coded mutants with mutants in the same genes from the Keio collection and found 90% had the same phenotype.

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