GenePage for the acrE gene of Escherichia coli K-12

Primary Gene Name: acrE
EcoGene Accession Number: EG10266
K-12 Gene Accession Number: ECK3252
MG1655 Gene Identifier: b3265
Gene Name Mnemonic: Acridine
Alternate Gene Symbols: envC
Description: AcrEF-TolC efflux pump, multidrug/solvent resistance; membrane-fusion lipoprotein
  # bp Upstream # bp Downstream
MW: 41317.68 ---------385 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 3413864
Left Intergenic Region

Name: acrS_acrE

Length: 398 bp gap

Orientation: Divergent

Left_end: 3413466

Right_end: 3413863

Centisome: 73.54

Genomic Address
Clockwise
Minute or Centisome (%) = 73.55
Right End: 3415021
Right Intergenic Region

Name: acrE_acrF

Length: 11 bp gap

Orientation: Codirectional+

Left_end: 3415022

Right_end: 3415032

Centisome: 73.57

AcrE is attached to the inner membrane. AcrEF confers resistance to nalidixic acid, acriflavin, indole and solvents. acrE is an acrA paralog. May have role in cell division. The first 23 aa of AcrE constitute a type II signal peptide.

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BamHI EcoRI HindIII