GenePage for the accC gene of Escherichia coli K-12

Primary Gene Name: accC
EcoGene Accession Number: EG10276
K-12 Gene Accession Number: ECK3243
MG1655 Gene Identifier: b3256
Gene Name Mnemonic: Acetyl-CoA carboxylase
Alternate Gene Symbols: fabG
Description: Acetyl-CoA carboxylase, biotin carboxylase (BC) subunit
  # bp Upstream # bp Downstream
Verified Start MW: 49320.74 ---------449 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 3405917
Left Intergenic Region

Name: accB_accC

Length: 10 bp gap

Orientation: Codirectional+

Left_end: 3405907

Right_end: 3405916

Centisome: 73.38

Genomic Address
Clockwise
Minute or Centisome (%) = 73.38
Right End: 3407266
Right Intergenic Region

Name: accC_yhdT

Length: 108 bp gap

Orientation: Codirectional+

Left_end: 3407267

Right_end: 3407374

Centisome: 73.41

accC mutations result in negative cooperativity with respect to the substrate bicarbonate. accC mutations affecting Arg 338 reveal arginine plays a role in carboxyl transfer to biotin.

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BamHI EcoRI HindIII