GenePage for the hypB gene of Escherichia coli K-12

Primary Gene Name: hypB
EcoGene Accession Number: EG10484
K-12 Gene Accession Number: ECK2722
MG1655 Gene Identifier: b2727
Gene Name Mnemonic: Hydrogenase pleiotropic
Alternate Gene Symbols: hydB; hydE
Description: Required for metallocenter assembly in Hydrogenases 1,2,3; guanine-nucleotide-binding protein; Ni donor for Hyd-3 large subunit; homodimeric
  # bp Upstream # bp Downstream
Verified Start MW: 31565.04 ---------290 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 2851001
Left Intergenic Region

Name: hypA_hypB

Length: 3 bp gap

Orientation: Codirectional+

Left_end: 2850998

Right_end: 2851000

Centisome: 61.42

Genomic Address
Clockwise
Minute or Centisome (%) = 61.42
Right End: 2851873
Right Intergenic Region

Name: hypB_hypC

Length: 10 bp overlap

Orientation: Codirectional+

Left_end: 2851864

Right_end: 2851873

Centisome: 61.44

hypB mutants are pheotypically suppressed by added Ni. HypB has a low level GTPase activity. HypA and HypB form a complex (Atanassova, 2005).

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BamHI EcoRI HindIII