GenePage for the acpH gene of Escherichia coli K-12

Primary Gene Name: acpH
EcoGene Accession Number: EG11095
K-12 Gene Accession Number: ECK0398
MG1655 Gene Identifier: b0404
Gene Name Mnemonic: Acyl carrier protein
Alternate Gene Symbols: acpD; yajB
Description: Acyl carrier protein (ACP) phosphodiesterase; ACP hydrolyase
  # bp Upstream # bp Downstream
MW: 22961.10 ---------193 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 424337
Left Intergenic Region

Name: malZ_acpH

Length: 4 bp gap

Orientation: Convergent

Left_end: 424333

Right_end: 424336

Centisome: 9.14

Genomic Address
Counterclockwise
Minute or Centisome (%) = 9.14
Right End: 424918
Right Intergenic Region

Name: acpH_queA

Length: 92 bp gap

Orientation: Divergent

Left_end: 424919

Right_end: 425010

Centisome: 9.15

AcpH is required for turnover of the acyl carrier protein (ACP) prosthetic group 4'-phosphopanthetheine at Ser36 in vivo. Structural modeling and site-directed mutagenesis experiments indicate that the AcpH/DUF479/COG3124 family are members of the HD superfamily of metal-dependent phosphohydrolases, although lacking a usually conserved His residue (Thomas, 2006).

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BamHI EcoRI HindIII