GenePage for the fau gene of Escherichia coli K-12

Primary Gene Name: fau
EcoGene Accession Number: EG11158
K-12 Gene Accession Number: ECK2907
MG1655 Gene Identifier: b2912
Gene Name Mnemonic: Folinic acid utilization
Alternate Gene Symbols: ygfA
Description: 5-formyltetrahydrofolate cycloligase, folinic acid catabolism; also known as 5,10-methenyltetrahydrofolate synthase (MTHFS)
  # bp Upstream # bp Downstream
MW: 21105.43 ---------182 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 3056241
Left Intergenic Region

Name: ssrS_fau

Length: 75 bp gap

Orientation: Codirectional+

Left_end: 3056166

Right_end: 3056240

Centisome: 65.84

Genomic Address
Clockwise
Minute or Centisome (%) = 65.84
Right End: 3056789
Right Intergenic Region

Name: fau_sibC

Length: 59 bp gap

Orientation: Codirectional+

Left_end: 3056790

Right_end: 3056848

Centisome: 65.86

Although enzyme activity has not been measured directly in E. coli, the accumulation of 5-CHO-THF (folinic acid ) in the fau(ygfA) mutant is diagnostic for 5-formyltetrahydrofolate cycloligase activity (Jeanguenin, 2010). A deletion of fau(ygfA) is sensitive to sulfonamide antifolate drugs (Ogwang, 2011). fau(ygfA) is induced during biofilm formation.

Go to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePage

BamHI EcoRI HindIII