GenePage for the hdeA gene of Escherichia coli K-12

Primary Gene Name: hdeA
EcoGene Accession Number: EG11398
K-12 Gene Accession Number: ECK3494
MG1655 Gene Identifier: b3510
Gene Name Mnemonic: hns-dependent expression
Alternate Gene Symbols: yhhC; yhiB
Description: Periplasmic chaperone of acid-denatured proteins; H-NS repressed
  # bp Upstream # bp Downstream
Verified Start MW: 11857.63 ---------110 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 3656408
Left Intergenic Region

Name: hdeB_hdeA

Length: 115 bp gap

Orientation: Codirectional-

Left_end: 3656293

Right_end: 3656407

Centisome: 78.77

Genomic Address
Counterclockwise
Minute or Centisome (%) = 78.77
Right End: 3656740
Right Intergenic Region

Name: hdeA_hdeD

Length: 254 bp gap

Orientation: Divergent

Left_end: 3656741

Right_end: 3656994

Centisome: 78.78

Overexpression causes abnormal biofilm architecture. Acid-inducible and important for acid survival. HdeA and HdeB are both involved in periplasmic protein solubilization at pH 3; HdeA is involved in periplasmic protein solubilization at pH 2 (Kern, 2006).

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BamHI EcoRI HindIII