GenePage for the cpxP gene of Escherichia coli K-12

Primary Gene Name: cpxP
EcoGene Accession Number: EG11872
K-12 Gene Accession Number: ECK3906
MG1655 Gene Identifier: b4484, b3913
Gene Name Mnemonic: Conjugative plasmid expression
Alternate Gene Symbols: yiiO
Description: Inhibitor of the cpx response; periplasmic adaptor protein, targets some proteins to DegP; dimeric
  # bp Upstream # bp Downstream
MW: 18965.25 ---------166 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 4105820
Left Intergenic Region

Name: cpxR_cpxP

Length: 149 bp gap

Orientation: Divergent

Left_end: 4105671

Right_end: 4105819

Centisome: 88.45

Genomic Address
Clockwise
Minute or Centisome (%) = 88.46
Right End: 4106320
Right Intergenic Region

Name: cpxP_cpxQ

Length: 9 bp gap

Orientation: Codirectional+

Left_end: 4106321

Right_end: 4106329

Centisome: 88.47

CpxP is involved in feedback inhibition of Cpx signal transduction. cpxP is induced in alkaline pH; CpxAR-regulated. CpxP and chaperone Spy are paralogs. CpxP suppresses toxic envelope protein effects. The first 21 aa of CpxP are predicted to be a type I signal peptide.

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BamHI EcoRI HindIII