GenePage for the feoB gene of Escherichia coli K-12

Primary Gene Name: feoB
EcoGene Accession Number: EG12102
K-12 Gene Accession Number: ECK3396
MG1655 Gene Identifier: b3409
Gene Name Mnemonic: FErOus iron transport
Alternate Gene Symbols: None
Description: Putative ferrous iron permease with GTP-binding domain
  # bp Upstream # bp Downstream
MW: 84473.66 ---------773 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 3540407
Left Intergenic Region

Name: feoA_feoB

Length: 16 bp gap

Orientation: Codirectional+

Left_end: 3540391

Right_end: 3540406

Centisome: 76.27

Genomic Address
Clockwise
Minute or Centisome (%) = 76.27
Right End: 3542728
Right Intergenic Region

Name: feoB_feoC

Length: 1 bp overlap

Orientation: Codirectional+

Left_end: 3542728

Right_end: 3542728

Centisome: 76.32

The FeoB GTPase activity is stimulated 5-fold by KCl and is not stimulated by FeoA addition (Lau, 2013). The GTPase actvity of the FeoB N-terminal G domain is required for ferrous iron uptake; it slowly hydrolyzes its bound GTP. FeoB may be a primordial archetype of G protein-regulated membrane proteins. Fur regulon. FNR regulon. An feoB mutant is unable to colonize the mouse intestine.

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BamHI EcoRI HindIII