GenePage for the bcsC gene of Escherichia coli K-12

Primary Gene Name: bcsC
EcoGene Accession Number: EG12257
K-12 Gene Accession Number: ECK3515
MG1655 Gene Identifier: b3530
Gene Name Mnemonic: Bacterial cellulose synthesis
Alternate Gene Symbols: yhjL
Description: Oxidase involved in cellulose production, contains TPR repeats
  # bp Upstream # bp Downstream
MW: 127723.92 ---------1157 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 3685700
Left Intergenic Region

Name: yhjK_bcsC

Length: 81 bp gap

Orientation: Codirectional-

Left_end: 3685619

Right_end: 3685699

Centisome: 79.40

Genomic Address
Minute or Centisome (%) = 79.40
Right End: 3689173
Right Intergenic Region

Name: bcsC_bcsZ

Length: 19 bp overlap

Orientation: Codirectional-

Left_end: 3689155

Right_end: 3689173

Centisome: 79.48

The bcsQ' domestication in-frame stop codon pseudogene defect in K-12 strain W3110 has been repaired, restoring cellulose production, colony morphology, biofilm architecture, and the divergent bcs operons' functions to a presumably wildtype status (Serra, 2013). The presence of an in-frame stop codon mutation in the bcsQ' gene abolishes cellulose production and bcs divergent operon function in E. coli K-12. The first 23 aa of BcsC are predicted to be a type I signal peptide.

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