GenePage for the bamA gene of Escherichia coli K-12
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Primary Gene Name: bamA EcoGene Accession Number: EG12676 K-12 Gene Accession Number: ECK0176 MG1655 Gene Identifier: b0177 |
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Gene Name Mnemonic: Beta-barrel assembly machine Alternate Gene Symbols: ecfK; omp85(N.m.); yaeT; yzzN; yzzY Description: Outer membrane protein required for OM biogenesis; in BamABCDE complex; forms pores; PORTA repeats |
| Verified Start | MW: 90552.77 ---------810 aa |
Pre-Run BlastP UniProt Pre-Run BlastP NR+Env |
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Left End: 197928 Left Intergenic Region Name: rseP_bamA Length: 29 bp gap Orientation: Codirectional+ Left_end: 197899 Right_end: 197927 Centisome: 4.26 |
Genomic Address Clockwise Minute or Centisome (%) = 4.26 |
Right End: 200360 Right Intergenic Region Name: bamA_skp Length: 121 bp gap Orientation: Codirectional+ Left_end: 200361 Right_end: 200481 Centisome: 4.32 |
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BamA has a C-terminal beta-barrel OM protein domain and an N-terminal periplasmic domain with five PORTA (polypeptide transport-associated) repeats that bind OM substrate peptides (Gatsos, 2008, Knowles, 2008; Ward, 2009). bamA is an essential gene. The ATG at codon 3 could be the true start codon. bamA is the last gene in the ispU-cdsA-rseP-bamA operon. HT_Cmplx49_Mem: DamX+BamA. ytfM and bamA are paralogs. An erroneous inner membrane localization may indicate binding to an inner membrane protein or cross-contamination (Lopez-Campistrous, 2005). otherPDB(H.ducreyi): 4K3C (Noinaj, 2014). otherPDB(N.gonorrhoeae): 4K3B (Noinaj, 2013).
