GenePage for the higA gene of Escherichia coli K-12

Primary Gene Name: higA
EcoGene Accession Number: EG12724
K-12 Gene Accession Number: ECK3072
MG1655 Gene Identifier: b3082
Gene Name Mnemonic: Host inhibition of growth
Alternate Gene Symbols: ygjM
Description: Antitoxin for HigB toxin
  # bp Upstream # bp Downstream
MW: 14995.42 ---------138 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 3233728
Left Intergenic Region

Name: fadH_higA

Length: 44 bp gap

Orientation: Convergent

Left_end: 3233684

Right_end: 3233727

Centisome: 69.67

Genomic Address
Counterclockwise
Minute or Centisome (%) = 69.67
Right End: 3234144
Right Intergenic Region

Name: higA_higB

Length: 4 bp overlap

Orientation: Codirectional-

Left_end: 3234141

Right_end: 3234144

Centisome: 69.68

The crystal structure of E. coli CFT073 YddM has been determined (PDB 2ICP AND 2ICT) but it is identical (94/94) to the YddM sequence of MG1655; the YddM structure is misidentified as the structure of the related paralog HigA antitoxin (Arbing, 2010). PF01381 family.

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BamHI EcoRI HindIII