GenePage for the frlC gene of Escherichia coli K-12

Primary Gene Name: frlC
EcoGene Accession Number: EG12910
K-12 Gene Accession Number: ECK3360
MG1655 Gene Identifier: b4474, b3373, b3372
Gene Name Mnemonic: FRuctoseLysine
Alternate Gene Symbols: yhfO; yhfP
Description: Fructoselysine 3-epimerase; interconverts fructoselysine and psicoselysine, allowing psicoselysine catabolism via the frl pathway
  # bp Upstream # bp Downstream
MW: 31168.83 ---------276 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 3502340
Left Intergenic Region

Name: frlB_frlC

Length: 49 bp gap

Orientation: Codirectional+

Left_end: 3502291

Right_end: 3502339

Centisome: 75.45

Genomic Address
Clockwise
Minute or Centisome (%) = 75.45
Right End: 3503170
Right Intergenic Region

Name: frlC_frlD

Length: 4 bp overlap

Orientation: Codirectional+

Left_end: 3503167

Right_end: 3503170

Centisome: 75.47

The putative frameshift that disrupted yhfO into two ORFs has been re-sequenced in K-12 and has now been corrected (E. Van Shaftin, personal comm.) fusing yhfO and the old yhfP into one new ORF, renamed as frlC. The "C" at position 3500308 has been removed. The Genbank entry U00096 now also has this correction, and the previous ALT_INIT, so the frlC status is OK now.

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BamHI EcoRI HindIII