GenePage for the csgC gene of Escherichia coli K-12

Primary Gene Name: csgC
EcoGene Accession Number: EG13414
K-12 Gene Accession Number: ECK1029
MG1655 Gene Identifier: b1043
Gene Name Mnemonic: Curlin sigma S-dependent growth
Alternate Gene Symbols: agfC(S.t.); ycdE
Description: Curli assembly protein
  # bp Upstream # bp Downstream
MW: 11966.65 ---------110 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 1104961
Left Intergenic Region

Name: csgA_csgC

Length: 58 bp gap

Orientation: Codirectional+

Left_end: 1104903

Right_end: 1104960

Centisome: 23.80

Genomic Address
Clockwise
Minute or Centisome (%) = 23.81
Right End: 1105293
Right Intergenic Region

Name: csgC_ymdA

Length: 120 bp gap

Orientation: Codirectional+

Left_end: 1105294

Right_end: 1105413

Centisome: 23.81

The overexpressed Salmonella AfgC(CsgC) protein is localized in the periplasm and has the first 8 amino acids removed, however SignalP does not predict this signal (Gibson, 2007). SignalP analysis is consistent with CsgC having an uncleaved signal anchor which may be subsequently cleaved by an intramembrane or periplasmic protease. Alternatively, the csgC signal peptide may be a valid type I signal peptide that is anomalous and was not represented in the SignalP training set.

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BamHI EcoRI HindIII