GenePage for the cdgI gene of Escherichia coli K-12

Primary Gene Name: cdgI
EcoGene Accession Number: EG13495
K-12 Gene Accession Number: ECK1783
MG1655 Gene Identifier: b1785
Gene Name Mnemonic: Cyclic-di-GMP
Alternate Gene Symbols: yeaI
Description: Inactive diguanylate cyclase, membrane-anchored
  # bp Upstream # bp Downstream
MW: 56101.44 ---------491 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 1870385
Left Intergenic Region

Name: yeaH_cdgI

Length: 146 bp gap

Orientation: Codirectional+

Left_end: 1870239

Right_end: 1870384

Centisome: 40.29

Genomic Address
Clockwise
Minute or Centisome (%) = 40.30
Right End: 1871860
Right Intergenic Region

Name: cdgI_yeaJ

Length: 180 bp gap

Orientation: Codirectional+

Left_end: 1871861

Right_end: 1872040

Centisome: 40.33

The GGDEF motif for YeaI is EGEVF and the putative diguanylate cyclase domain is likely to be non-functional (Sommerfeldt, 2009). YeaI has an N-terminal integral membrane domain with 8 predicted TM helices reminiscent of the MASE TM signaling domains found in other c-di-GMP domain proteins. The yeaI promoter region binds FNR (Federowicz, 2014).

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BamHI EcoRI HindIII