GenePage for the ecpB gene of Escherichia coli K-12

Primary Gene Name: ecpB
EcoGene Accession Number: EG13564
K-12 Gene Accession Number: ECK0291
MG1655 Gene Identifier: b0292
Gene Name Mnemonic: E. coli common pilus
Alternate Gene Symbols: matC; yagY
Description: Periplasmic pilus chaperone required for ECP formation
  # bp Upstream # bp Downstream
MW: 24516.99 ---------222 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 309358
Left Intergenic Region

Name: ecpC_ecpB

Length: 25 bp gap

Orientation: Codirectional-

Left_end: 309333

Right_end: 309357

Centisome: 6.66

Genomic Address
Counterclockwise
Minute or Centisome (%) = 6.66
Right End: 310026
Right Intergenic Region

Name: ecpB_ecpA

Length: 57 bp gap

Orientation: Codirectional-

Left_end: 310027

Right_end: 310083

Centisome: 6.68

The O18ac:K1:H7 NMEC ecpRAB(matABC) genes are required for E. coli common pilus (Mat fimbria) formation when cloned in K-12; (Pouttu, 2001).The E. coli O18ac:K1:H7 NMEC ecpABCDE(matBCDEF) genes are all individually required for E. coli common pilus (ECP) formation in the pathogenic E.coli NMEC strains and ECP production enhances low-temperature biofilm formation in NMEC and and also in K-12 when the silent ecp operon is expressed; ecpR(matA) mRNA was detected in K-12, but not ecpAB(matBC) mRNA (Pouttu, 2001; Lehti, 2010; Garnett, 2012). The first 20 aa of EcpB are predicted to be a signal peptide. EcpB and EcpE are paralogous proteins with PapD-like N-terminal domains (PF00345).

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BamHI EcoRI HindIII