GenePage for the essD gene of Escherichia coli K-12

Primary Gene Name: essD
EcoGene Accession Number: EG13634
K-12 Gene Accession Number: ECK0545
MG1655 Gene Identifier: b0554
Gene Name Mnemonic: S protein
Alternate Gene Symbols: ybcR
Description: Prophage DLP12 S holin lysis protein
  # bp Upstream # bp Downstream
MW: 7778.06 ---------71 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 577398
Left Intergenic Region

Name: nmpC_essD

Length: 572 bp gap

Orientation: Divergent

Left_end: 576826

Right_end: 577397

Centisome: 12.43

Genomic Address
Clockwise
Minute or Centisome (%) = 12.44
Right End: 577613
Right Intergenic Region

Name: essD_rrrD

Length: 1 bp overlap

Orientation: Codirectional+

Left_end: 577613

Right_end: 577613

Centisome: 12.44

The probable transcription antiterminator QuuD(YbaQ) binds to the essD promoter region and increases transcription of the lysis cassette genes essD(ybcQ), rrrD(ybcS), rzpD(ybcT) and rzoD; quuD(ybaQ) mutants have reduced biofilm formation via down-regulation of curlin(CsgA); overexpression of QuuD(YbaQ) increases cell lysis and biofilm formation (Rueggeberg, 2013). Overexpression of EssD-GFP causes cell death (Srividhya, 2012).

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BamHI EcoRI HindIII