GenePage for the glsB gene of Escherichia coli K-12

Primary Gene Name: glsB
EcoGene Accession Number: EG13816
K-12 Gene Accession Number: ECK1517
MG1655 Gene Identifier: b1524
Gene Name Mnemonic: GLutanimaSe
Alternate Gene Symbols: glsA2; yneH
Description: Glutaminase 2; GlsA2
  # bp Upstream # bp Downstream
MW: 33515.59 ---------308 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 1612325
Left Intergenic Region

Name: yneG_glsB

Length: 1 bp overlap

Orientation: Codirectional-

Left_end: 1612325

Right_end: 1612325

Centisome: 34.74

Genomic Address
Counterclockwise
Minute or Centisome (%) = 34.74
Right End: 1613251
Right Intergenic Region

Name: glsB_sad

Length: 63 bp gap

Orientation: Codirectional-

Left_end: 1613252

Right_end: 1613314

Centisome: 34.76

Two glutaminases have been purified and biochemically characterized from E. coli B. glsB(yneH) is required for growth on l-glutamine as the sole source of carbon and nitrogen and might contribute to acid resistance (Brown, 2008). glsB(yneH) was identified as a multicopy suppressor of both serA and serC deletions (Patrick, 2007).

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BamHI EcoRI HindIII