GenePage for the hxpB gene of Escherichia coli K-12
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Primary Gene Name: hxpB EcoGene Accession Number: EG13988 K-12 Gene Accession Number: ECK1725 MG1655 Gene Identifier: b1727 |
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Gene Name Mnemonic: Hexitol phosphatase Alternate Gene Symbols: yniC Description: Hexitol phosphatase B; 2-deoxyglucose-6-P phosphatase |
| MW: 24330.24 ---------222 aa |
Pre-Run BlastP UniProt Pre-Run BlastP NR+Env |
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Left End: 1809380 Left Intergenic Region Name: yniB_hxpB Length: 146 bp gap Orientation: Divergent Left_end: 1809234 Right_end: 1809379 Centisome: 38.98 |
Genomic Address Clockwise Minute or Centisome (%) = 38.98 |
Right End: 1810048 Right Intergenic Region Name: hxpB_ydjM Length: 162 bp gap Orientation: Codirectional+ Left_end: 1810049 Right_end: 1810210 Centisome: 39.00 |
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HxpB catalyzes the dephosphorylation of D-mannitol 1-phosphate and D-sorbitol 6-phosphate (Sévin, 2017). hxpB(yniC) mutants are hypersensitive to 2-deoxyglucose; overproduction of HxpB(YniC) confers 2-deoxyglucose resistance; HxpB(YniC) has additional in vitro substrates mannose-6-P phosphate, 2-deoxyribose-5-P, ribose-5-P, and glucose-6-P (Kuznetsova, 2005; Kuznetsova, 2006). HAD superfamily. HT_Cmplx36_Cyt: Mog+YniC.
