GenePage for the hxpB gene of Escherichia coli K-12

Primary Gene Name: hxpB
EcoGene Accession Number: EG13988
K-12 Gene Accession Number: ECK1725
MG1655 Gene Identifier: b1727
Gene Name Mnemonic: Hexitol phosphatase
Alternate Gene Symbols: yniC
Description: Hexitol phosphatase B; 2-deoxyglucose-6-P phosphatase
  # bp Upstream # bp Downstream
MW: 24330.24 ---------222 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 1809380
Left Intergenic Region

Name: yniB_hxpB

Length: 146 bp gap

Orientation: Divergent

Left_end: 1809234

Right_end: 1809379

Centisome: 38.98

Genomic Address
Clockwise
Minute or Centisome (%) = 38.98
Right End: 1810048
Right Intergenic Region

Name: hxpB_ydjM

Length: 162 bp gap

Orientation: Codirectional+

Left_end: 1810049

Right_end: 1810210

Centisome: 39.00

HxpB catalyzes the dephosphorylation of D-mannitol 1-phosphate and D-sorbitol 6-phosphate (Sévin, 2017). hxpB(yniC) mutants are hypersensitive to 2-deoxyglucose; overproduction of HxpB(YniC) confers 2-deoxyglucose resistance; HxpB(YniC) has additional in vitro substrates mannose-6-P phosphate, 2-deoxyribose-5-P, ribose-5-P, and glucose-6-P (Kuznetsova, 2005; Kuznetsova, 2006). HAD superfamily. HT_Cmplx36_Cyt: Mog+YniC.

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BamHI EcoRI HindIII