GenePage for the arnD gene of Escherichia coli K-12

Primary Gene Name: arnD
EcoGene Accession Number: EG14092
K-12 Gene Accession Number: ECK2249
MG1655 Gene Identifier: b2256
Gene Name Mnemonic: ara4N (4-amino-4-deoxy-L-arabinose)
Alternate Gene Symbols: pbgP4(S.t.); pmrJ(S.t.); yfbH
Description: Undecaprenyl phosphate-aminoarabinose deformylase
  # bp Upstream # bp Downstream
MW: 33111.79 ---------296 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 2370018
Left Intergenic Region

Name: arnA_arnD

Length: 4 bp overlap

Orientation: Codirectional+

Left_end: 2370018

Right_end: 2370021

Centisome: 51.06

Genomic Address
Clockwise
Minute or Centisome (%) = 51.06
Right End: 2370908
Right Intergenic Region

Name: arnD_arnT

Length: 1 bp overlap

Orientation: Codirectional+

Left_end: 2370908

Right_end: 2370908

Centisome: 51.08

An arnD mutant strain accumulates formylated C55-P-LAra4N and blocks C55-P-LAra4N production, supporting the deformylase functional assignment (S.D. Breazeale, A.A. Ribeiro, A.L. McClerren, and C.R.H. Raetz, in preparation, personal communication November, 2007). ArnD is involved in the modification of lipid A phosphates with aminoarabinose that is required for polymyxin B and cationic antimicrobial peptide resistance. The arnBCADTEF operon promoter region binds FNR and arnBCADTEF expression is repressed by FNR (Federowicz, 2014). Chitin deacetylase family (COG0726).

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BamHI EcoRI HindIII