GenePage for the hokE gene of Escherichia coli K-12

Primary Gene Name: hokE
EcoGene Accession Number: EG14302
K-12 Gene Accession Number: ECK0574
MG1655 Gene Identifier: b4415
Gene Name Mnemonic: Host killing
Alternate Gene Symbols: ybdY
Description: Putative small toxic membrane polypeptide; homologous to plasmid-encoded plasmid stabilization toxins regulated by antisense RNA; regulatory antisense sRNA antitoxin is SokE
  # bp Upstream # bp Downstream
MW: 5563.74 ---------50 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 607836
Left Intergenic Region

Name: sokE_hokE

Length: 43 bp gap

Orientation: Codirectional+

Left_end: 607793

Right_end: 607835

Centisome: 13.09

Genomic Address
Clockwise
Minute or Centisome (%) = 13.10
Right End: 607988
Right Intergenic Region

Name: hokE_insL2

Length: 76 bp gap

Orientation: Codirectional+

Left_end: 607989

Right_end: 608064

Centisome: 13.10

Although sokE and hokE are intact, the start of the regulatory peptide gene mokE is missing from this remnant hok/mok locus, so the mokE (and hence hokE) is not expressed and the frame cannot be determined to annotate a pseudogene. LexA regulon. IS186B is inserted downstream of the hokE gene in K-12.

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BamHI EcoRI HindIII