GenePage for the arnE gene of Escherichia coli K-12

Primary Gene Name: arnE
EcoGene Accession Number: EG14344
K-12 Gene Accession Number: ECK2251
MG1655 Gene Identifier: b4544
Gene Name Mnemonic: ara4N (4-amino-4-deoxy-L-arabinose)
Alternate Gene Symbols: pbgE2(S.t.); pmrL(S.t.); yfbW
Description: Undecaprenyl phosphate-alpha-L-ara4N exporter; flippase ArnEF subunit
  # bp Upstream # bp Downstream
MW: 12191.95 ---------111 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 2372557
Left Intergenic Region

Name: arnT_arnE

Length: 4 bp overlap

Orientation: Codirectional+

Left_end: 2372557

Right_end: 2372560

Centisome: 51.11

Genomic Address
Clockwise
Minute or Centisome (%) = 51.11
Right End: 2372892
Right Intergenic Region

Name: arnE_arnF

Length: 1 bp overlap

Orientation: Codirectional+

Left_end: 2372892

Right_end: 2372892

Centisome: 51.12

Export via ArnEF is required for the modification of lipid A phosphates with aminoarabinose that is needed for polymyxin B and cationic antimicrobial peptide resistance (Yan, 2007). ArnEF is also known as the probable 4-amino-4-deoxy-L-arabinose(Ara4N)-phosphoundecaprenol flippase. The arnBCADTEF operon promoter region binds FNR and arnBCADTEF expression is repressed by FNR (Federowicz, 2014).

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BamHI EcoRI HindIII