GenePage for the frmA gene of Escherichia coli K-12

Primary Gene Name: frmA
EcoGene Accession Number: EG50010
K-12 Gene Accession Number: ECK0353
MG1655 Gene Identifier: b0356
Gene Name Mnemonic: Formaldehyde
Alternate Gene Symbols: adhC
Description: Glutathione-dependent formaldehyde dehydrogenase
  # bp Upstream # bp Downstream
Verified Start MW: 39358.99 ---------369 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 378462
Left Intergenic Region

Name: frmB_frmA

Length: 93 bp gap

Orientation: Codirectional-

Left_end: 378369

Right_end: 378461

Centisome: 8.15

Genomic Address
Counterclockwise
Minute or Centisome (%) = 8.15
Right End: 379571
Right Intergenic Region

Name: frmA_frmR

Length: 34 bp gap

Orientation: Codirectional-

Left_end: 379572

Right_end: 379605

Centisome: 8.18

The frmRAB operon is negatively regulated by frmR, is induced by formaldehyde, and probably degrades formaldehyde. Formaldehyde spontaneously forms S-hydroxymethylglutathione, which FrmA then converts to S-formylglutathione.

Go to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePage

BamHI EcoRI HindIII